MRGPRX2, atopic dermatitis, and red man syndrome

Vancoymycin causes red man syndrome, an itchy erythematous eruption involving the face, neck, and upper torso. Atopic dermatitis also manifests itch and erythema, and staphylococcus δ-toxin contributes to this process. The antibiotic and toxin each provoke mast cell degranulation but the mechanism h