First total synthesis of new diglycosides, neohancoside A, and B from Cynanchum hancockianum

Abstract First total synthesis of monoterpene diglycosides, neohancosides A ( 1 ) and B ( 2 ) from Cynanchum hancockianum were achieved stereoselectively using fluoride as a glycosyl donor. The absolute configurations of 1 and 2 were determined by enzymatic degradation of synthetic intermediates