雷公藤内酯醇对内毒素激活小鼠腹腔巨噬细胞分泌促炎症介质NO和IL-6的影响(英文)

Objective Tripterygium wilfordii Hook.f.has been used for centuries in traditional Chinese medicine to treat autoimmune disease associated with increased production of the pro-inflammatory cytokine.Triptolide(TP) is a compound originally purified from T.wilfordii Hook f.and it has potent anti-inflammatory and immunosuppressant activities.In this study,we investigated the effect of TP on secretion of NO and IL-6 in celiac macrophages (MΦ) activated by lipopolysaccharide (LPS) in Kunming mice.Methods Celiac M...