위장관 : 궤양성대장염의 (潰瘍性大腸炎) 임상적 (臨床的) 관찰

Ulcerative colitis is a diffuse inflammatory disease of the mucosal lining of the colon, but relatively rare in this country. Clinical studies of this disease are lacking in this country despite of the limited some observations of the surgical approach of it. we observed for purpose of clinical observation of twenty-eight patients with ulcerative colitis seen in this hospital from November 1968 to August 1986. 1) The most prevalent age group was ranged 30 to 49 and the mean age approximated as 36.4. Occurrence of male to female was 1.3:1. 2) The most common initial symptom in these patients was diarrhea. The additional cardinal symptoms were included as mucobloody diarrhea, abdominal pain and tenesmus as well as fever. 3) According to the anatomical site of the lesion in this disease, left colitis and proctitis were most common (79%) but pancolitis was few (29%). In a view point of the severity in this disease, the relapsing remission form was most common (54%) but the acute fulminating form included only two cases (7%). 4) Nineteen patients given the medical treatment in this disease were effective except three cases. The medical treatment was included with SASP with or without adrenal corticosteroid by the mouth or enema. The untoward action of the medical agents in these patients were minimal and transient. 5) Twelve patients had the surgical operation in our series. They were included as six cases with intestinal obstruction, two intestinal perforation, a case acute fulminating ulcerative colitis, and three cases refractory to the medica1 treatment, respectively.