Adventitial cystic disease

Adventitial cystic disease (ACD), also known as cystic adventitial disease, is a rare condition characterized by cystic lesions of the non-axial blood vessels adjacent to joints.1,2 ACD was first described by Atkins and Key in 1947.3 Since that time, about 350 cases of ACD have been reported in the English literature. ACD usually involves the popliteal artery, but other great arteries and veins of the lower and upper extremities can also be involved. Intermittent claudication of the legs and limb pain are the main clinical presenting symptoms. Here, we report a 30-year-old male with ACD who was successfully treated by total excision of the lesion and graft replacement. The histopathologic findings and possible pathogenesis of this disease are discussed. Case Report