Hypernephroma of the Ovary

Summary 1. Hypernephroid tumors, i.e., yellow tumors containing large lipid filled cells, of the ovary have been described over the course of many years. The tumors differ considerably in appearance and behavior. Some have been masculinizing; a few have produced precocious puberty. There has been and still is much discussion about the histogenesis of these tumors, some favoring an adrenal rest; some a lutein cell origin. There are many contradictions in each point of view, and great confusion about these tumors still exists. It is highly questionable if they do constitute a definitive group. 2. A case of such a tumor is presented, which is believed to have been secondary to a renal hypernephroma removed eleven years before. The ovarian tumor bled into a large serous cyst of the ovary and caused fatal intraperitoneal hemorrhage. 3. Renal hypernephrornas and their metastases are bizarre in their behavior. Long time-intervals and peculiar manifestations from the metastases have been the subject of many papers. Ovarian metastases are very rare. This case constitutes the third, or possibly the fourth, on record.