In vivo Photothermal Optical Coherence Tomography of Gold Nanorods in the Mouse Eye

Maryse Lapierre-Landry,Andrew Y. Gordon,John S. Penn,Melissa C. Skala

In vivo Photothermal Optical Coherence Tomography of Gold Nanorods in the Mouse Eye

2017

Maryse Lapierre-Landry
Andrew Y. Gordon
John S. Penn
Melissa C. Skala

We have performed in vivo photothermal optical coherence tomography (PT-OCT) in the mouse eye for the first time. PT-OCT signal increased significantly in neovascular lesions after systemic injection of gold nanorods as compared to control.

Keywords:

Preclinical imaging
Biomedical engineering
In vivo
Optic nerve
Molecular imaging
Photothermal therapy
Optics
Optical coherence tomography
Materials science
Nanorod
Image registration

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