The clinical significance of serum Apo-E detected by immunoturbidimetric assay on patients with hyperlipidemia

Objective To discuss the clinical significance of the detection of serum Apo-E level of patients with hyperlipidemia (HLP).Methods The serum Apo-E,TC,HDL-C,LDL-C,TG,Apo-Al and Apo-B in 120 patients with HLP and 130 health adults were detected by immunoturbidimetry.Results The serum Apo-E level in patients with HLP was significantly higher than that in normal group (55.2 ± 14.3mg/L,40.4 ± 12.5mg /L;P ＜0.01 ),and was significant positive correlated with the TG and Apo-B (r=0.538,0.432;P＜0.05).The Apo-E level was a risk factor of coronary heart disease and atherosclerosis.Conclusions The serum Apo-E levels in patients with HLP were significant increased.The detection of serum Apo-E level can be used as a diagnosis index of cardio-cerebral vascular disease. Key words: Immunoturbidimetric assay; Apo-E; Hyperlipidemia ; Cardio-cerebral vascular disease