the Research of Kidney Aquaporin-2 mRNA Expression in Kidney-Qi Deficiency Model Rats

Objective:To observe the effects of kidney aquaporin-2 expression in kidney-Qi deficiency model rats. Method:Twenty healthy SD rats were divided into the model group and the control group at radom. The method of RT-PCR was used to observe the expression of aquaporin-2 in kidney.Results: kidney AQP2 mRNA expression in the kidney-Qi deficiency model rats is decreased to compare with the control group (P 0.01). Conclusion: kidney-Qi deficiency model rats kidney AQP2 mRNA expression is reduced, thus causes the kidney AQP2 expression to reduce, causes the urine quntantity to increase. This experiment has provided the experimental basis for the theory of "the kidney host water" of the traditional Chinese medicine.