A new label-free and turn-on fluorescence probe for hydrogen peroxide and glucose detection based on DNA–silver nanoclusters
2015
We have developed a reliable, sensitive, label-free and turn-on sensor for H2O2 and glucose based on the cleavage of ssDNA by ˙OH and the fluorescence enhancement effect when guanine-rich (G-rich) DNA sequences are in proximity to DNA–silver nanoclusters (DNA–Ag NCs). In addition, we have also proved that ˙OH is indeed produced in the sensing system by adding antioxidants.
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