Activities of ketone body utilising enzymes in tissues of fed and fasted sheep

The activities of 3-hydroxybutyrate dehydrogenase, 3-ketoacid CoA-transferase and acetyl-CoA acetyltransferase have been measured in the kidney, heart and brain of fed and four-day fasted ewes. The results indicate that there is a decrease in the capacity of these organs to catabolise ketone bodies in fasting ketosis.