«ГИПЕРТОНИЯ БЕЛОГО ХАЛАТА» ПРИ НЕДИФФЕРЕНЦИРОВАННОЙ ДИСПЛАЗИИ СОЕДИНИТЕЛЬНОЙ ТКАНИ: КОНСТИТУЦИОНАЛЬНАЯ ХАРАКТЕРИСТИКА И ЭНДОТЕЛИАЛЬНОAТРОМБОЦИТАРНАЯ ДИСФУНКЦИЯ

In total, 15 patients with nоn-differentiated connective tissue dysplasia (CTD) and white coat hypertension (WCH), 10 WCH-free individuals, and 10 healthy volunteers aged 18-30 years were examined. CTD and WCH patients had greater body weight and body mass index than DCT individuals without WCH. CTD and WCH combination was associated with increased levels of adrenalin and ADP-induced platelet aggregation, endothelin-1, as well as with reduced 6-keto-prostaglandin F 1α (6-keto-PGF 1α ) concentration. In CTD without WCH, collagen-induced platelet aggregation and Willebrand factor activity were decreased.