PP.25.21: MATRIX METALLOPROTEINASE-2 AND TISSUE INHIBITOR OF METALLOPROTEINASE-2 ARE ASSOCIATED WITH HYPERTENSION TO THE PROGRESSION OF CHRONIC KIDNEY DISEASE IN PATIENTS WITH PRIMARY CHRONIC GLOMERULONEPHRITIS

Objective:Matrix metalloproteinase-2 (MMP-2) is considered to be the main enzyme that degrades collagen type-IV (col-IV) and has been implicated in chronic kidney disease (CKD) and cardiovascular disease (CVD). Tissue inhibitor of metalloproteinase-2 (TIMP-2) participates in nephron morphogenesis an