Analgesic effect comparison of preoperative application of flurbiprofen axetil and ropivacaine after laparoscopic cholecystectomy

2013 
Objective To investigate the analgesic effects of the preoperative application of flurbiprofen axetil and ropivacaine after the laparoscopic cholecystectomy. Methods 154 patients who had received laparoscopic cholecystectomy in our hospital were selected and divided into the control group and the observation group according to the anesthetic method. The control group contained 77 patients and the observation group contained 77 patients. The observation group received preoperative intravenous infusion of flurbiprofen axetil and the control group received preoperative local injection of ropivacaine. Using the visual analog scale, the 2, 4, 8, 12 and 24-hour pain scores and analgesia scores and the post-analgesic adverse reactions of the two groups were compared. Results The 2, 4, 8, 12 and 24-hour pain scores and analgesia scores of the observation group were (2.7±0.5), (2.8±1.2), (2.9±1.8), (2.2±0.7) and (1.6±0.5), which were significantly lower than those of the control group, with statistically significant differences (P 0.05). The total incidence of adverse reactions of the observation group was 22.07%, which was significantly lower than that of the control group, with statistically significant differences (P 0.05). Conclusion In terms of the analgesic effect after the laparoscopic cholecystectomy, flurbiprofen axetil is better than ropivacaine and has lower incidence of adverse reactions, thereby worthy of clinical promotion and application.
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