Infecţia cu Mycoplasma în determinismul naşterii premature – review din literatură

Preterm labor is responsible for most cases of neonatal death. In most of these cases, the causes have not been established, although several risk factors have been incriminated. My­co­plas­ma hominis is a common vaginal organism that is associated with bacterial vaginosis. The bacterium is con­si­dered inoffensive for the most part in nonpregnant wo­men, but it can cause intraamniotic infections which are associated with inflammation, preterm premature rup­ture of membranes, and preterm birth. The role of these genital tract habitants in their infection during preg­nan­cy and their capacity to invade placental and fe­tal tissue are discussed. In particular, the role of some of these or­ga­nisms in prematurity may be mechanistically as­so­cia­ted to their ability to induce inflammatory cytokines, thus trig­gering pathways causing to premature labor. A re­view of this intensifying research of mycoplasmas in re­la­tion to pregnancy lead to several questions and findings that will be important to examine in future research.