Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing

Mina Nikanjam,Clinton F. Stewart,C. H. Takimoto,Timothy W. Synold,Orren Beaty,Maryam Fouladi,Edmund V. Capparelli

Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing

2015

Mina Nikanjam
Clinton F. Stewart
C. H. Takimoto
Timothy W. Synold
Orren Beaty
Maryam Fouladi
Edmund V. Capparelli

Purpose To characterize the determinants of variability for oxaliplatin pharmacokinetics including age, renal function, and hepatic function in children and adults.

Keywords:

Creatinine
Renal function
Pharmacology
Young adult
Dosing
Covariate
Population
Oxaliplatin
Medicine
Pharmacokinetics
pediatric cancer

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