Coexpression networks identify brain region-specific enhancer RNAs in the human brain
2015
Identifying enhancers regions has been primarily focused on model organisms and human transformed cell lines. This study characterizes enhancer RNA (eRNA) expression in the human brain by identifying brain region–specific eRNAs and assessing eRNA-gene coexpression interactions. The authors further demonstrate an enrichment of brain eRNAs for autism-associated genetic variants.
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