Analysis on the Use of Antimicrobials before and after Special Administration

Objective: To analyze the use of antibiotics in the patients of Tianmen First People's Hospital before and after Special Administration of rational use of antimirobial agents in order to promote clinical rational drug use.Methods: A total of 1680 medical records and 100 records of type I incision operation(thyroid/mammary gland/hernia/closed fractures) were randomly selected from January 2010 to December 2011.Statistically analyze the antibiotic use rate,total antibiotic use density,rate of etiological examination,DDDs,and DUI before and after Special Administration.And the antibiotic use of type I incision operation were evaluated.Results: The use rate of antibiotics was 68.5% in inpatients,and total antibiotic use density was calculated as 49.8 DDD/100 patient days before Special Administration,and respectively 56.2% and 49.8DDD after,showing obvious drop(P0.05).Before Special Administration,the DUI of 4 kinds of antibacterials were slightly greater than 1.0,which were in the following order: cefoperazone/sulbactamcefalotin= cephazolincefuroxime.After Special Administration,the DUI of 2 kinds were slightly greater than 1.0,which were sulbenicillin cefoperazone/sulbactam.The use rate of antibiotics for patients of type I incision operation were also reduced,and tha accordance rate of treating courses and drug rational user rate were increased(P0.05).Conclusion: The use of antibiotics in our hospital basically met the requirement of Special Work Plan for Clinical Antibiotics Use,but more efforts should be made to make a progress,for example,to be more careful in choosing Type I incision operation,course of treatment and cure with medicine,to enhance monitoring the use of antibiotics in Type I incision operation.Only in these ways could clinical rational drug use be economically and effectively enhanced.