Preparation method of (R)-lansoprazole sustained-release capsule

The invention relates to an (R)-lansoprazole sustained-release capsule and a preparation method thereof and belongs to the field of sustained-release preparations, and particularly relates to a preparation method of an acid-sensitive proton pump inhibitor sustained-release enteric-coated pellets. The capsule is filled with two kinds of pellets of which the releasing speed are different, one is enteric-coated quick-release pellets and the other one is enteric-coated sustained-release pellets. In the invention, damage on the (R)-lansoprazole is avoided and the (R)-lansoprazole is orientedly released in intestinal tracts, so that the capsule is quick in action, is prolonged in medicine effect and is improved in bioavailability, and is mainly improved significantly in stability of medicine active molecules in the preparation.