Homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita like phenotypes

TO THE EDITOR: Dyskeratosis congenita (DC) and its severe form, Hoyeraal-Hreidarsson syndrome (HHS), are rare and have life-threatening failure of hematopoiesis. Typically, DC patients present with disease features such as nail dystrophy, oral leukoplakia, and abnormal skin pigmentation along with