Effect of 3-thienylalanine-ornithine-proline, new sulfur-containing angiotensin-converting enzyme inhibitor on blood pressure and oxidative stress in spontaneously hypertensive rats.

Abstract:Sulfur-containing angiotensin-converting enzyme (ACE) inhibitors have an edge over other inhibitors in improving endothelial dysfunction and reducing oxidative stress. In this study, effect of new sulfur-containing ACE inhibitor, 3-thienylalanine-ornithine-proline (TOP), was studied on bloo