APPLICATION OF THE FIT FOR DETECTION OF COLORECTAL PATHOLOGY. EXPERIENCE OF YAROSLAVL REGION

2017 
AIM. To evaluate the effectiveness and diagnostic value of FIT «Colon View Hb and Hb/Hp» («Colon View»). MATERIALS AND METHODS. The study included 588 patients who underwent FIT «Golon View Hb and Hb/Hp» («Golon View»). RESULTS. When performing a three-time «Colon View» the diagnostic accuracy of the procedure increased for both -for hemoglobin (sensitivity -92,86 specificity - 73,17) and for hemoglobin-haptoglobin complex (sensitivity - 88,1 specificity - 63,41), p<0,05. However, only 39,4 % of patients with a positive «Colon View» test agreed to undergo a colonoscopy. CONCLUSION. Three-fold execution of the FIT «Colon View» increases the diagnostic accuracy of the method, as for Hb andfor Hb/Hp. However, the effectiveness of the test using hemoglobin is higher. Joint use of two indicators (Hb and Hb/Hp) further improves the precision of this model for screening large adenomas and CRC.
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