Evaluation of QRS dispersion and its association withtachyarrhythmia events in patients with implantedcardiac resynchronization therapy defibrillator device
2018
Introduction: Heart failure (HF) is one of the major problems of health
system in the countries. In a subgroup of these patients, cardiac
resynchronization therapy defibrillator (CRT-D) improves the quality of life by
enhancing the function of the left ventricle (LV) and preventing of
arrhythmias. The present study intends to discuss the effect of CRT-D on the
QRS dispersion, as a predisposing factor to arrhythmias.
Methods: 45 patients treated with CRT-D during 2012-2015
were enrolled in this study. QRS dispersion in various V-V delays was measured
and its association with the incidence of arrhythmias, at least six months
after insertion, was assessed.
Results: The
results showed that QRS dispersion in the intrinsic mode was significantly
lower than the other modes of the CRT-D device (P < 0.001). Besides, it was
revealed that mean QRS duration in the intrinsic mode had a higher association
with arrhythmic events than max QRS duration. QRS dispersion after CRT-D
implantation had a significant increase compared to the intrinsic mode.
However, it did not correlate with the arithmetic events. Further decrease in
the duration of QRS after CRT-D implantation improved arrhythmias.
Conclusion:
QRS dispersion after CRT-D implantation is not an
indicative of arrhythmia
risk, and a decrease in the duration of QRS had a more significant effect on
the incidence
of arrhythmias.
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