Antibacterial Activity Of Tetrahydro-b-Carboline-3-Carboxylic Acid And Its Derivatives

1,2,3,4-Tetrahydro-I²-carboline-3-carboxylic acid (THBCC) and three of its derivatives, 1-methyl-THBCC, 1-pyridoxyl-THBCC and 1-methyl-1-carboxyl-THBCC have been synthesised by Pictet-Spengler condensation and their antibacterial activity was evaluated against five bacterial strains by the agar well diffusion method. MIC values were determined by the tube dilution method.