Imaging Evaluation of Cutaneous Lymphoma Using Functional and Structural Imaging

Primary cutaneous lymphoma is the second most frequent extranodal lymphoma. Cutaneous T-cell lymphoma with approximately 65% frequency is the most common histology seen in these patients. Imaging studies are greatly used in lymphoma diagnosis, staging, and follow-up. Although structural imaging such as CT scan has been commonly used in studying lymphomas, it has limited capability in determining cutaneous involvement and extracutaneous involvement in normal sized lymph nodes and enlarged reactive lymph nodes. Fluorodeoxyglucose positron emission tomography (FDG-PET) has been shown of great value in primary evaluation, staging, response assessment, and detecting disease recurrence in cutaneous lymphoma.