Physical fatigue and the morfofunctional state of myocardium in experimental chronic stress

The relationship between skeletal muscle fatigue and morpho-functional alterations in the myocardium was analyzed for the first time in Wistar male rats exposed to chronic stress. Post traumatic stress disorder (PTSD) was associated with signs of increased oxidative stress, which apparently induced the changes in cardiomyocyte structural components and the acceleration of skeletal and muscular fatigue.