Arrhythmias in Right Heart Failure due to Pulmonary Hypertension

The clinical relevance of cardiac arrhythmias has not been systematically studied in patients with right heart failure and pulmonary arterial hypertension (PAH) despite being important contributors to morbidity and mortality. Electro-anatomical remodeling of the right ventricle and right atrium in response to longstanding pressure and volume overload, resulting from altered autonomics, repolarization abnormalities, and ischemia, may be the underlying substrate predisposing to enhanced arrhythmogenicity in patients with right heart failure and PAH.