FDG PET-CT in the Management of Primary Breast Lymphoma

Primary breast lymphoma (PBL) is a rare diseaseand its management differs from other breast cancers. The purpose of thisstudy is to evaluate the role of FDG PET-CT in the management of PBL. Wecarried out 16 PET-CT scans and reviewed the literature.A total of 16 FDG PET-CT scans were done in 8 female patients withPBL with a median age of 49 years (range: 27–68). Of the 16 PET-CT scans,1 scan was done for primary diagnosis and staging (1 patient), 2 for staging(2 patients), 7 for evaluation of treatment response (6 patients), and 6 fordetecting recurrence (4 patients). PET-CT image interpretation and analysiswere performed qualitatively (visually) and semiquantitatively using stan-dardized uptake value (SUV). Absence of uptake in the postchemotherapyfollow-up PET-CT scan was considered as a complete response, and a fall ofmore than 50% of baseline SUV was considered as a significant response.