Atheromatous plaque initiation and growth

Abstract We present a multiphysical model to understand atheromatous plaque growth. The model was based on the physics of blood flow in the arterial lumen (Navier–Stokes equations and Darcy's law) coupled to a convection-diffusion-reaction equation to model exchange between lumen and arterial wall. The Kedem-Katchalsky theory was used to model intercellular coupling via the membranes.