GUILLAIN-BARRE SYNDROME OCCURRENCE IN PATIENTS WITH FRONTAL EPILEPSY AND VASCULITIS

Guillain-Barre syndrome (GBS) is an acute quickly progressing autoimmune disease of peripheral nervous system. Its etiology and pathogenesis are not studied till now and, therefore, remain the subject of discussions. In modern studies, the problems of comorbidity of this disease with different pathologies are discussed. The cases of simultaneous occurrence of GBS with myositis, transverse myelitis, mycoplasmal pneumonia are described. In this paper there is presented a case report on GBS occurrence in patients with frontal epilepsy and vasculitis. Marked immunocompomise of the body, participation of multiple viral-bacterial agents allows to speak about the available genetic predisposition to different types of immunopathological reactions, in particular GBS. The question of whether these diseases are comorbid or these are different processes needs further study, discussion and practical alertness in relation to these states.