Aesthetic aspects of skin ageing, prevention and local treatment

Abstract Skin ageing is a complex biologic process influenced by a combination of intrinsic and extrinsic factors. Ageing skin shows wrinkles, uneven tone, loss of elasticity, and thinning. Skin health is considered one of the principal factors representing overall “well-being” and the perception of “health” in humans; therefore, anti-ageing strategies to combat both ageing signs and dysfunction have been developed over the last decades. Understanding the mechanism behind skin ageing is required for elucidation of the mechanism of action and, hence, the potential benefits of the claimed anti-ageing products. In this review, preventive measurements, cosmetologic strategies and photoprotection (systemic antioxidants, UV filters), as well as the mechanisms of action and the effectiveness of topical pharmaceutical agents, such as antioxidants (vitamins, polyphenols, and flavonoids) and cell regulators (retinols, peptides, hormones, and botanicals) are presented.