A case of antisynthetase syndrome with elevated serum CA19-9 associated with interstitial lung disease

A 70-year-old Japanese woman was referred to our hospital in 2015 for a one-year history of skin eruptions and elevated creatine kinase (CK). She had been followed for mild interstitial lung disease (ILD) without treatment for some years. Physical examination showed mechanic's hand on her fingers (figure 1A). Although she exhibited Raynaud's phenomenon and proximal muscle weakness, she had neither palmar papules nor systemic symptoms, such as fever and arthropathy. Laboratory investigations showed [...]