Medical treatment of urethral prolapse in the premenarchal female

Abstract Urethral prolapse, the circumferential protrusion of urethral mucosa through the urethral meatus, often presents in the premenarchal female as a large, friable mass. Some traditional therapies have included excision or cautery. A series of 13 premenarchal females presented with urethral prolapse and were treated medically at the Chicago Lying-in Hospital. All patients had resolution of signs and symptoms within 4 weeks of initiation of therapy. No relapses or recurrences were noted. Medical therapy of urethral prolapse in the premenarchal female is a safe and successful alternative to surgery.