Development of chronic bronchitis and possibilities of objective evaluation of its premorbid states

A total of 163 patients with prebronchitis underwent clinical, laboratory and functional examinations from the standpoint of revealing and assessment of risk factors. Based on the data obtained the etiopathogenetic variants of the formation of chronic bronchitis (prebronchitis) were established: exogenous, endogenous and combined. The characteristic features of the variants were defined from the point of view of clinical, immunological and functional studies.