Power Spectral Analysis of Heart Rate Variability in Rats as a Quantitative Tool in the PK-PD Analysis of the Parasympatholytic Activity of Atropine
2001
Purpose. To utilize power spectral analysis (PSA) of heart rate variability (HRV) as a pharmacodynamic (PD) measure of atropine parasympathetic effect, and to model the kinetics of action.
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