A15156 G protein-coupled receptor kinase 2 is a novel modulator of oxidative stress and prostanoids production in adipocytes in hypertension

Objectives:Oxidative stress and prostanoids released from adipose tissue participate in vascular dysfunction in hypertension and obesity. G protein-coupled receptor kinase 2 (GRK2) is increased in obesity and hypertension and regulates adiposity. We investigated the role of GRK2 in oxidative stress