Selective solid phase extraction of chloroacetamide herbicides from environmental water samples by amphiphilic magnetic molecularly imprinted polymers

Abstract In this study, a novel amphiphilic magnetic molecularly imprinted polymers (MMIPs) have been prepared by using Fe 3 O 4 microspheres as the magnetic core, 4-vinyl pyridine (4-VP) and alkenyl glycosides glucose (AGG) as functional co-monomers. Fe 3 O 4 microspheres were directly encapsulated by the polymer without any surface modification in the distillation-precipitation polymerization. The morphology and composition of MMIPs were characterized by X-ray diffraction (XRD), vibrating sample magnetometry (VSM), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Binding property and magnetic separation ability were systematically investigated through the equilibrium binding experiments. The feasibility of magnetic molecular imprinted solid phase extraction (MMISPE) was investigated for the selective enrichment of chloroacetamide herbicides from environmental water samples. The developed MMISPE-HPLC method exhibited good linearity (0.1–200 μg L −1 ), low limit of detection (0.03–0.06 μg L −1 ), and good precision (RSD