Intramembranous structure of the postsynaptic membrane in the rat sensorimotor cortex

Intramembranous structure of the postsynaptic membrane of the axodendritic synapses in the rat sensorimotor cortex was examined by means of freeze-etching technique. Perforated and non-perforated aggregates of particles were found at the extracellular half (E-face) of the postsynaptic membrane. To study correlation between membrane structure and synaptic plasticity we compared size and particle packing density in both type aggregates of particles at the E-face of the postsynaptic dendritic spine membrane. The results are discussed in terms of plasticity on the synaptic contact zone (SCZ) at the postsynaptic membrane of the excitatory axospinous synapses.