Beitrag zur Partialsynthese 18-oxygenierter Cortexone II. Synthese von 18-Oxo-cortexon Über Steroide 231. Mitteilung†‡

18-Oxocortexone, a potential metabolite of 11-deoxy-corticosterone and precursor of aldosterone has been synthesized, starting from 3β-hydroxy-5-pregnene-20-one acetate via subsequent functionalization at positions 18 and 21.