Decades of Research and Advancements on Fabrication and Applications of Silk Fibroin Blended Hydrogels

The Hydrogels are tunable three dimensional polymer network attractive for their rich hydrophilicity along with structural similarity with the extracellular matrix that provide a cell proliferation and facilitate rapid cell to cell communication. These Hydrogels are largely focussed by many researchers in the field of medicine due to its capacity to act as scaffold for tissue regeneration, as injectable Hydrogel for sustained drug delivery, in encapsulation of the enzymes and many more. These are prepared by either natural or artificial polymer or both and the nature of selection of polymer depends on its functional characteristics. In this review we reminisce different fabrication techniques and applications of Silk Fibroin (SF) blended with other polymers. SF acts as an attractive class due to excellent mechanical strength, biocompatibility that doesn’t trigger any adverse immunological reaction and manageable biodegradation; in addition this Silk biomaterial has been used for suturing from past many centuries.