Alveolar sac analysis of 3D human lung microstructure using synchrotron radiation micro-CT

Three-dimensional microstructural analysis of human infant, adult, and diseased lungs can help us understand lung growth and disease progression. Three-dimensional analysis of alveolar sacs and alveolar ducts is fundamental. However, it has not been done completely due to technical limitations. In this study, we will acquire ultra-high resolution 3D CT images by large-field synchrotron radiation micro-CT and reveal the 3D structure of alveolar septa and alveolar sacs by CT image analysis.