Short axial length and hyperopic refractive error are risk factors of central serous chorioretinopathy

Background/aims To evaluate the axial length (AL) and refractive status in central serous chorioretinopathy (CSC). Methods This retrospective observational case series involved 140 patients with CSC (180 eyes) and 78 age-matched and gender-matched control subjects. A detailed ophthalmic examination was performed, including an interferometer measurement of AL. Multimodal imaging comprised colour fundus photography, fluorescein angiography, indocyanine green angiography, fundus autofluorescence photography and spectral domain optical coherence tomography. Results Eighty eyes of 40 patients were categorised into the bilateral-CSC (b-CSC) group and 100 eyes of 100 patients were categorised into the unilateral-CSC (u-CSC) group. AL of the b-CSC (23.19 mm) and u-CSC (23.75 mm) groups was significantly shorter than that of the control (24.85 mm) group (p Conclusion Anatomical features, such as shorter AL and greater SE, may be associated with the pathogenesis of CSC.