Total Laryngectomy with Radiotherapy in Stage T3-T4

Objective: Evaluation of the result of treatment with total laryngectomy and complementary radiotherapy in patients with cancer of the larynx in stage T3- T4 N0M0. Analysis of the impact of the primary cancer localization, feature G and T, unradical result of the surgery treatment.Method: The study population included 136 patients with cancer of the larynx in stadium T3-T4 N0M0 treated with curative intent by total laryngectomy with complementary radiotherapy. T3 was in 61 patients, T4 was in 75 patients.Results: In coregression analysis of multivariate failure did not show the statistically related to the recurrence and death P > 0.1. Two- and 5-year disease-free survival was for all group adequately 83% and 76%. Two- and 5-year disease-free survival in cases T3 and T4 was adequately 88% and 76%. In patients with primary localization in glottis 2- and 5-year disease-free survival was adequately 81% and 73% in cases supraglottis 88% and 81%.Conclusion: The primary cancer localization, feature G and T, unr...