2,6-dione - piperazine (piperidine) derivatives and their Applications

The present invention discloses a 2,6-diketone - piperazine (piperidine) derivatives and their use, the derivatives may be applied to central nervous system disorders medicament for preventing or treating. Animal test results show, in two MK-801-induced animal model of climbing high activity and apomorphine-induced ED50 smaller, more action, and more ED50 in animal models of catalepsy, therapeutic index greater. The derivative is a compound having the formula (I) or a salt thereof: