Retroviral transduction of human dihydropyrimidine dehydrogenase cDNA confers resistance to 5-fluorouracil in murine hematopoietic progenitor cells and human CD34+-enriched peripheral blood progenitor cells.

Naoko Takebe,Shi-Cheng Zhao,Ali Ugur Ural,Martin R. Johnson,Debabrata Banerjee,Robert B. Diasio,Joseph R. Bertino

Retroviral transduction of human dihydropyrimidine dehydrogenase cDNA confers resistance to 5-fluorouracil in murine hematopoietic progenitor cells and human CD34+-enriched peripheral blood progenitor cells.

2001

Naoko Takebe
Shi-Cheng Zhao
Ali Ugur Ural
Martin R. Johnson
Debabrata Banerjee
Robert B. Diasio
Joseph R. Bertino

Retroviral transduction of human dihydropyrimidine dehydrogenase cDNA confers resistance to 5-fluorouracil in murine hematopoietic progenitor cells and human CD34 + -enriched peripheral blood progenitor cells

Keywords:

Drug resistance
Virology
Molecular biology
Biology
Progenitor cell
CD34
Fluorouracil
Dihydropyrimidine dehydrogenase
Transduction (genetics)
Viral vector
Complementary DNA
Western blot
Bone marrow
Gene

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