Análise comparativa entre a cicatrização de ferida cutânea tratada com adesivo de éster de cianocrilato (SuperBonder®) e sutura intradérmica com náilon em ratos da linhagem Wistar

The ethyl-cyanoacrylate which is an acid cyanoacrilic ester of short chain it has been extensively used in cutaneous wound closure. The objective of this study was to evaluate the efficacy of ethyl cyanoacrylate in cutaneous excision repair of Wistar male rats. 16 Wister rats were used and divided in two groups, each with eight animals. The rats were premedicated with xylazine (3mg/kg IM) and ketamine (70mg/kg IM) and trichotomised manually. Antiasepsis was achieved with 70% alcohol solution and 0,5% chlorhexidine followed by placement of discarded sterile fields. A longitudinal incision was made to five centimeters on the back of each rats which were closed using ECA or sutures (4-0 nylon). The rats were observed 1st, 2nd, 3rd, 7 th, and 15th. The tissue adhesives presented the largest dehiscence levels. Ethyl cyanoacrylate was adequately tolerated in this study with no necrosis, allergic reactions, or infections. Ethyl cyanoacrylate presented several advantages over suture use, including low complication rates and aid in the suture of incisions.