Desulfurization of biotin and epibiotin sulfoxides with nickel boride: Analysis of the stereoselectivity through [2H] NMR in a polypeptide liquid crystal

Abstract Reduction of biotin or epibiotin sulfoxides with nickel boride and deuterated reagents affords as major products bideuterated dethiobiotin. Deuterium localisation by [ 2 H] NMR in a chiral liquid crystal allows the analysis of the stereoselectivity of the reaction.