Characteristic responses of a 1,2-di-myristoyl-sn-glycero-3-phosphocholine molecular layer to polymeric surfactants at an air/water interface

Abstract Phospholipid molecular layers mixed with polymeric surfactants (PS) composed of ethylene oxide and/or propylene oxide monomers were investigated experimentally to clarify the effect of the chemical structure of the PS on the monolayers. The surface pressure ( Π ) – surface area ( A ) isotherm for phospholipid (1,2-dimyristoyl- sn -glycero-3-phosphocholine (DMPC)) changed characteristically depending on the chemical structure of the PS. Differential scanning calorimetry and attenuated total reflection Fourier transform infrared spectroscopy were used to evaluate the interaction between DMPC and PS molecules.