Keratosis pilaris rubra and keratosis pilaris atrophicans faciei treated with pulsed dye laser: report of 10 cases.

Background  Keratosis pilaris rubra (KPR) and keratosis pilaris atrophicans faciei (KPAF) are both keratinization disorders characterized by erythema and keratotic follicular papules usually located on cheeks, forehead, chin and eyebrows. Topical keratolytics, vitamin D3 analogues, antibiotics, topical and oral retinoids have been used with limited results. As this condition can be socially very limiting, the need for an effective treatment has led to the use of other technologies such as pulsed dye laser (PDL) or intense pulsed light. Objective  The aim of this study was to assess the efficacy and safety of PDL in patients with KPR or KPAF. Methods  Ten patients with KPR or KPAF were treated with two to seven sessions of PDL at 595-nm wavelength. Laser therapy was performed using a spot size of 7 or 10 mm, a pulse duration of 0.5 or 1.5 ms and a fluence from 5 to 9 J/cm2. Two dermatologists evaluated treatment effectiveness by means of photographs of the patients before starting and after finishing the therapy. Results  Complete resolution of erythema was achieved in three patients; clearance of erythema was > 75% in the other seven patients. Transient purpura was present in all patients for about 2 weeks and one patient presented postinflammatory hyperpigmentation for 7 months. Conclusion  We consider that PDL is a good option for the treatment of KPR and KPAF. A marked reduction in erythema is achieved in all patients with a low incidence of side effects.