Consumo de antibióticos sistémicos en Valladolid (1996-2000)

espanolEl presente estudio longitudinal retrospectivo tuvo como objetivo analizar la evolucion del consumo de antibioticos de uso sistemico a lo largo del quinquenio 1996-2000 en la provincia de Valladolid. Se determino el consumo de antibioticos de uso sistemico de acuerdo con la dosis diaria definida. Dicho consumo presento un aumento progresivo durante los cuatro primeros anos del estudio, disminuyendo de forma importante en el ano 2000. Por subgrupos, las penicilinas de amplio espectro fueron las determinantes de casi el 60% del consumo, siendo por tanto la causa de la mencionada evolucion. Los macrolidos representaron el 16,4% del consumo, aumentando durante todo el periodo estudiado. Las quinolonas, con el 9,3% del total, presentaron un incremento lento y mantenido. Las cefalosporinas supusieron el 8,1% del consumo, disminuyendo desde el ano 1998. Del estudio se desprende que las penicilinas de amplio espectro son los antibioticos sistemicos mas consumidos en la poblacion estudiada, aunque hemos observado una tendencia hacia una disminucion de su uso y un aumento de los macrolidos y las quinolonas. EnglishA longitudinal retrospective study was conducted to analyze the changes in the use of systemic antibiotics from 1996 to 2000 in the province of Valladolid, Spain. The use of systemic antibiotics was determined according to the defined daily dose and showed a progressive increase during the first four years of the study, followed by a large decrease in the year 2000. When examined by subgroup, wide spectrum penicillins accounted for almost 60% of the antibiotics consumed, and were therefore responsible for this change. Macrolides represented 16.4% of the consumption, which increased during the whole study period. Quinolones, with 9.3% of the total, showed a slow but steady increase. Cephalosporins accounted for 8.1%, with their use decreasing since 1998. It was concluded that wide spectrum penicillins were the most used systemic antibiotics in the study population, although a decreasing trend in their use and an increase in the use of macrolides and quinolones was observed.